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- Target Alle RNF20 Antikörper anzeigen
- RNF20 (Ring Finger Protein 20 (RNF20))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser RNF20 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein G.
- Immunogen
- This RNF20 antibody is generated from a mouse immunized with a recombinant protein of human RNF20.
- Klon
- 4C6
- Isotyp
- IgG1
- Top Product
- Discover our top product RNF20 Primärantikörper
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anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibody
RNF20 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (Internal Region) antibodyRNF20 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibodyRNF20 Reaktivität: Human IP Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1E4 unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-260) antibodyRNF20 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 576-625) antibodyRNF20 Reaktivität: Human, Maus, Hund, Rind (Kuh), Meerschweinchen, Schwein, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 108-157) antibodyRNF20 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (N-Term) antibodyRNF20 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:300-5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- RNF20 (Ring Finger Protein 20 (RNF20))
- Andere Bezeichnung
- RNF20 (RNF20 Produkte)
- Synonyme
- 4833430L21Rik antikoerper, AW540162 antikoerper, C79397 antikoerper, mKIAA4116 antikoerper, BRE1 antikoerper, BRE1A antikoerper, hBRE1 antikoerper, ring finger protein 20 antikoerper, RNF20 antikoerper, Rnf20 antikoerper
- Hintergrund
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Synonyms: BRE1, BRE1A, hBRE1, E3 ubiquitin-protein ligase BRE1A, BRE1-A, RING finger protein 20, RNF20
Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.
- Gen-ID
- 56254
- UniProt
- Q5VTR2
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