RYK Antikörper
Kurzübersicht für RYK Antikörper (ABIN4913824)
Target
Alle RYK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein G.
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Immunogen
- This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK.
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Isotyp
- IgG1
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Applikationshinweise
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WB 1:300-5000
FCM 1:20-100 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
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Andere Bezeichnung
- RYK
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Hintergrund
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Synonyms: JTK5, RYK1, JTK5A, D3S3195, Tyrosine-protein kinase RYK, RYK
Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
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Gen-ID
- 6259
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UniProt
- P34925
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Pathways
- RTK Signalweg, WNT Signalweg, Regulation of Cell Size
Target
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