TBP Antikörper
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- Target Alle TBP Antikörper anzeigen
- TBP (TATA Box Binding Protein (TBP))
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Reaktivität
- Human, Maus, Ratte, Cynomolgus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TBP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus, Ratte
- Kreuzreaktivität (Details)
- Cynomolgus Monkey
- Aufreinigung
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogen
- Purified His-tagged TBP protein was used to produced this monoclonal antibody.
- Klon
- 8C4
- Isotyp
- IgG1
- Top Product
- Discover our top product TBP Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- TBP (TATA Box Binding Protein (TBP))
- Andere Bezeichnung
- TBP (TBP Produkte)
- Hintergrund
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Synonyms: HDL4, GTF2D, SCA17, TFIID, GTF2D1, TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit, TBP, TF2D
Background: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
- Gen-ID
- 6908
- UniProt
- P20226
- Pathways
- WNT Signalweg
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