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USP11 Antikörper

USP11 Reaktivität: Human WB Wirt: Maus Monoclonal 2C9 unconjugated
Produktnummer ABIN4915064
  • Target Alle USP11 Antikörper anzeigen
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Reaktivität
    • 49
    • 13
    • 12
    • 1
    • 1
    Human
    Wirt
    • 43
    • 6
    • 1
    Maus
    Klonalität
    • 36
    • 14
    Monoklonal
    Konjugat
    • 26
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser USP11 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 21
    • 17
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11.
    Klon
    2C9
    Isotyp
    IgG1
    Top Product
    Discover our top product USP11 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Andere Bezeichnung
    USP11 (USP11 Produkte)
    Hintergrund

    Synonyms: UHX1, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11, USP11

    Background: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome (PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro) (PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, PubMed:20233726).

    Gen-ID
    8237
    UniProt
    P51784
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