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USP5 Antikörper

USP5 Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 13C4 unconjugated
Produktnummer ABIN4915071
  • Target Alle USP5 Antikörper anzeigen
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    Reaktivität
    • 39
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 32
    • 8
    Maus
    Klonalität
    • 33
    • 7
    Monoklonal
    Konjugat
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser USP5 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 17
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.
    Klon
    13C4
    Isotyp
    IgG1
    Top Product
    Discover our top product USP5 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    USP5 (Ubiquitin Specific Peptidase 5 (USP5))
    Andere Bezeichnung
    USP5 (USP5 Produkte)
    Synonyme
    ISOT antikoerper, AA407472 antikoerper, ISOT-1 antikoerper, Ucht antikoerper, ubiquitin specific peptidase 5 antikoerper, ubiquitin carboxyl-terminal hydrolase 5 antikoerper, ubiquitin carboxyl-terminal hydrolase 5, putative antikoerper, ubiquitin specific protease 5 antikoerper, ubiquitin specific peptidase 5 (isopeptidase T) antikoerper, USP5 antikoerper, CNH02890 antikoerper, EHI_049940 antikoerper, CC1G_12961 antikoerper, MCYG_01862 antikoerper, CGB_L3600C antikoerper, PY00546 antikoerper, Usp5 antikoerper
    Hintergrund

    Synonyms: ISOT, Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, USP5, USP 5, USP-5

    Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

    Gen-ID
    8078
    UniProt
    P45974
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