Rekombinanter Cadherin-16 Antikörper
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- Target Alle Cadherin-16 (CDH16) Antikörper anzeigen
- Cadherin-16 (CDH16)
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Cadherin-16 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Protein A affinity chromatography
- Immunogen
- Human protein was used as the immunogen for the recombinant Cadherin 16 antibody.
- Klon
- CDH16-1532R
- Isotyp
- IgG kappa
- Top Product
- Discover our top product CDH16 Primärantikörper
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- Applikationshinweise
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Optimal dilution of the recombinant Cadherin 16 antibody to be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/10e6 cells,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the recombinant Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- Cadherin-16 (CDH16)
- Andere Bezeichnung
- Cadherin 16 (CDH16 Produkte)
- Synonyme
- cadherin 16 antikoerper, CDH16 antikoerper, Cdh16 antikoerper
- Hintergrund
- Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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