Plakophilin 1 Antikörper (N-Term)

Produktnummer ABIN4949852

Produktdetails anti-Plakophilin 1 Antikörper

Target: Plakophilin 1 (PKP1)

Bindungsspezifität: AA 1-27, N-Term

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Plakophilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Protein G affinity chromatography

Immunogen: A N-terminal human recombinant protein fragment was used as the immunogen for the Plakophilin 1 antibody. Its epitope maps to between amino acids 1-27 of human PKP1.

Klon: 10B2

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Plakophilin 1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Plakophilin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Plakophilin 1

Target: Plakophilin 1 (PKP1)

Andere Bezeichnung: Plakophilin 1 (PKP1 Produkte)

Hintergrund: Recognizes a protein of 75  kDa, identified as Plakophilin 1 (PKP1). Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. PKP1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). PKP2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.