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ABI1 Antikörper

ABI1 Reaktivität: Human, Ratte, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4952702
  • Target Alle ABI1 Antikörper anzeigen
    ABI1 (Abl-Interactor 1 (ABI1))
    Reaktivität
    • 49
    • 36
    • 27
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 63
    • 3
    Kaninchen
    Klonalität
    • 63
    • 3
    Polyklonal
    Konjugat
    • 43
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABI1 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 18
    • 15
    • 15
    • 15
    • 13
    • 13
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    Antigen affinity
    Immunogen
    Amino acids HGVKWLKAKHGNNQPARTGTLSRTN of human SSH3BP1 were used as the immunogen for the SSH3BP1 antibody.
    Isotyp
    IgG
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    Discover our top product ABI1 Primärantikörper
  • Applikationshinweise
    Optimal dilution of the SSH3BP1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the SSH3BP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    ABI1 (Abl-Interactor 1 (ABI1))
    Andere Bezeichnung
    SSH3BP1 (ABI1 Produkte)
    Hintergrund
    SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.
    UniProt
    Q8IZP0
    Pathways
    RTK Signalweg, Response to Water Deprivation, ER-Nucleus Signaling
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