Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SMAD6 Antikörper (AA 358-386)

SMAD6 Reaktivität: Human WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032629
  • Target Alle SMAD6 Antikörper anzeigen
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    Bindungsspezifität
    • 15
    • 9
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 358-386
    Reaktivität
    • 51
    • 28
    • 11
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Wirt
    • 53
    • 14
    Kaninchen
    Klonalität
    • 55
    • 12
    Polyklonal
    Konjugat
    • 40
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMAD6 Antikörper ist unkonjugiert
    Applikation
    • 58
    • 39
    • 14
    • 13
    • 6
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 358-386 from the human protein was used as the immunogen for this SMAD6 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SMAD6 Primärantikörper
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the SMAD6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at 4°C for up to one month. For long term, aliquot the SMAD6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    Andere Bezeichnung
    SMAD6 (SMAD6 Produkte)
    Synonyme
    madh6 antikoerper, madh7 antikoerper, Xsmad6 antikoerper, hst17432 antikoerper, AOVD2 antikoerper, HsT17432 antikoerper, MADH6 antikoerper, MADH7 antikoerper, Madh6 antikoerper, b2b390Clo antikoerper, Smad6-like antikoerper, smad6 antikoerper, wu:fb22g05 antikoerper, SMAD family member 6 antikoerper, SMAD family member 6a antikoerper, smad6 antikoerper, SMAD6 antikoerper, Smad6 antikoerper, smad6a antikoerper
    Hintergrund
    SMAD6 acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [UniProt]
    UniProt
    O43541
    Pathways
    Chromatin Binding
Sie sind hier:
Kundenservice