SIRT6 Antikörper
-
- Target Alle SIRT6 Antikörper anzeigen
- SIRT6 (Sirtuin 6 (SIRT6))
-
Reaktivität
- Human, Maus, Ratte, Primate
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser SIRT6 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Aufreinigung
- Protein G affinity
- Immunogen
- A human recombinant protein was used as the immunogen for this SIRT6 antibody.
- Klon
- 6C9-D10-D3
- Isotyp
- IgG1
- Top Product
- Discover our top product SIRT6 Primärantikörper
-
-
- Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the SIRT6 antibody at -20°C.
-
- Target
- SIRT6 (Sirtuin 6 (SIRT6))
- Andere Bezeichnung
- SIRT6 (SIRT6 Produkte)
- Synonyme
- 2810449N18Rik antikoerper, AI043036 antikoerper, Sir2l6 antikoerper, SIR2L6 antikoerper, zgc:86729 antikoerper, sirtuin 6 antikoerper, sirtuin 6 S homeolog antikoerper, Sirt6 antikoerper, SIRT6 antikoerper, sirt6.S antikoerper, sirt6 antikoerper
- Hintergrund
- NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]
- UniProt
- Q8N6T7
-