ALPL Antikörper (AA 217-246)

Produktnummer ABIN3029909

Produktdetails anti-ALPL Antikörper

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Bindungsspezifität: AA 217-246

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALPL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung: Purified

Immunogen: A portion of amino acids 217-246 from human ALPL was used as the immunogen for this Alkaline Phosphatase antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Alkaline Phosphatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Alkaline Phosphatase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ALPL

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Andere Bezeichnung: Alkaline Phosphatase (liver) (ALPL Produkte)

Synonyme: ALP antikoerper, iap antikoerper, alpl antikoerper, AP-TNAP antikoerper, APTNAP antikoerper, HOPS antikoerper, TNAP antikoerper, TNSALP antikoerper, Akp-2 antikoerper, Akp2 antikoerper, PHOA antikoerper, TNS-AP antikoerper, alkaline phosphatase, liver/bone/kidney L homeolog antikoerper, alkaline phosphatase, liver/bone/kidney antikoerper, alkaline phosphatase, intestinal, gene 2 antikoerper, alkaline phosphatase, liver/bone/kidney pseudogene antikoerper, alpl.L antikoerper, ALPL antikoerper, alpi.2 antikoerper, LOC100031702 antikoerper, Alpl antikoerper

Hintergrund: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

UniProt: P05186