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LGR5 Antikörper (AA 605-638)

LGR5 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031605
  • Target Alle LGR5 Antikörper anzeigen
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    Bindungsspezifität
    • 16
    • 15
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 605-638
    Reaktivität
    • 99
    • 57
    • 49
    • 1
    • 1
    Human
    Wirt
    • 86
    • 13
    • 1
    Kaninchen
    Klonalität
    • 77
    • 23
    Polyklonal
    Konjugat
    • 46
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LGR5 Antikörper ist unkonjugiert
    Applikation
    • 73
    • 39
    • 20
    • 19
    • 18
    • 17
    • 14
    • 13
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 605-638 from the human protein was used as the immunogen for this anti-LGR5 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product LGR5 Primärantikörper
  • Applikationshinweise
    Titration of the anti-LGR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the anti-LGR5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    Andere Bezeichnung
    LGR5 (LGR5 Produkte)
    Synonyme
    lgr5-a antikoerper, lgr5a antikoerper, FEX antikoerper, Gpr49 antikoerper, GPR49 antikoerper, GPR67 antikoerper, GRP49 antikoerper, HG38 antikoerper, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antikoerper, leucine rich repeat containing G protein coupled receptor 5 antikoerper, leucine rich repeat containing G protein-coupled receptor 5 antikoerper, lgr5.L antikoerper, Lgr5 antikoerper, LGR5 antikoerper
    Hintergrund
    LGR5/GPR49 is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. [UniProt]
    UniProt
    O75473
    Pathways
    WNT Signalweg
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