ATF6B Antikörper (AA 560-589)

Produktnummer ABIN3029852

Produktdetails anti-ATF6B Antikörper

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Bindungsspezifität: AA 560-589

Reaktivität: Human, Maus, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ATF6 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ATF6 beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ATF6B

Target: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Andere Bezeichnung: ATF6 beta (ATF6B Produkte)

Synonyme: CREBL1 antikoerper, CREB-RP antikoerper, G13 antikoerper, AA617266 antikoerper, ATF6beta antikoerper, Creb-rp antikoerper, Crebl1 antikoerper, activating transcription factor 6 beta antikoerper, cyclic AMP-dependent transcription factor ATF-6 beta antikoerper, ATF6B antikoerper, LOC745411 antikoerper, Atf6b antikoerper

Hintergrund: ATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction