ATG12 Antikörper (AA 1-50)

Produktnummer ABIN3030084

Produktdetails anti-ATG12 Antikörper

Target: ATG12 (Autophagy Related 12 (ATG12))

Bindungsspezifität: AA 1-50

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1-50 from the human protein was used as the immunogen for this ATG12 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ATG12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ATG12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ATG12

Target: ATG12 (Autophagy Related 12 (ATG12))

Andere Bezeichnung: ATG12 (ATG12 Produkte)

Synonyme: APG12 antikoerper, APG12L antikoerper, FBR93 antikoerper, HAPG12 antikoerper, Apg12l antikoerper, AUTOPHAGY 12 antikoerper, AUTOPHAGY 12 B antikoerper, CG10861 antikoerper, Dmel\\CG10861 antikoerper, atg12 antikoerper, ATG12 antikoerper, apg12 antikoerper, DDBDRAFT_0185323 antikoerper, DDBDRAFT_0191412 antikoerper, DDB_0185323 antikoerper, DDB_0191412 antikoerper, 4931423H11Rik antikoerper, A330058M13Rik antikoerper, Atg12l antikoerper, AO090001000593 antikoerper, autophagy related 12 antikoerper, Ubiquitin-like superfamily protein antikoerper, Atg12p antikoerper, autophagy protein antikoerper, ubiquitin-like protein ATG12B antikoerper, autophagy associated protein Atg12 antikoerper, Autophagy-related 12 antikoerper, ATG12 autophagy related 12 homolog (S. cerevisiae) antikoerper, ATG12 autophagy related 12 homolog (S. cerevisiae) pseudogene antikoerper, autophagy associated ubiquitin-like modifier Atg12 antikoerper, hypothetical protein antikoerper, Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) antikoerper, autophagy protein 12 antikoerper, autophagy related 12 S homeolog antikoerper, autophagy-related protein 12 antikoerper, ATG12 antikoerper, Atg12 antikoerper, APG12B antikoerper, APG12 antikoerper, LOC9321066 antikoerper, apg12 antikoerper, atg12 antikoerper, LOC743425 antikoerper, CAALFM_C113950CA antikoerper, atg12.S antikoerper, ANI_1_922094 antikoerper, AOR_1_1064164 antikoerper

Hintergrund: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

APG12L/ATG12 is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.

UniProt: O94817

Pathways: Autophagie