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Beclin 1 Antikörper (AA 181-210)

BECN1 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030157
  • Target Alle Beclin 1 (BECN1) Antikörper anzeigen
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    Bindungsspezifität
    • 16
    • 15
    • 13
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-210
    Reaktivität
    • 161
    • 68
    • 55
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 127
    • 37
    • 2
    Kaninchen
    Klonalität
    • 125
    • 41
    Polyklonal
    Konjugat
    • 92
    • 13
    • 10
    • 9
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser Beclin 1 Antikörper ist unkonjugiert
    Applikation
    • 134
    • 72
    • 47
    • 37
    • 33
    • 26
    • 23
    • 17
    • 17
    • 14
    • 13
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität (Details)
    Expected species reactivity: Bovine, Chicken
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 181-210 from the human protein was used as the immunogen for this Beclin 1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product BECN1 Primärantikörper
  • Applikationshinweise
    Titration of the Beclin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the Beclin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    Andere Bezeichnung
    Beclin 1 (BECN1 Produkte)
    Hintergrund
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis. Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.
    UniProt
    Q14457
    Pathways
    Autophagie
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