Titration of the BMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the BMP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
OI13 antikoerper, PCOLC antikoerper, PCP antikoerper, PCP2 antikoerper, TLD antikoerper, Pcp antikoerper, Tld antikoerper, BMP1 antikoerper, submp antikoerper, tld antikoerper, xtld antikoerper, bmp-1 antikoerper, pcolc antikoerper, xbmp1 antikoerper, tolloid antikoerper, BMP-1 antikoerper, bmp1 antikoerper, bmp1a antikoerper, bone morphogenetic protein 1 antikoerper, Bone morphogenetic protein 1 antikoerper, bone morphogenetic protein 1 S homeolog antikoerper, bone morphogenetic protein 1, like antikoerper, BMP1 antikoerper, Bmp1 antikoerper, bmp1 antikoerper, bmp1.S antikoerper, bmp1l antikoerper
Hintergrund
The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.