CAMKK2
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Titration of the CAMKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the CAMKK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
CAMKK2
(Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
CAMKK antikoerper, CAMKKB antikoerper, 6330570N16Rik antikoerper, AW061083 antikoerper, mKIAA0787 antikoerper, camk2b antikoerper, fj90d04 antikoerper, wu:fj90d04 antikoerper, si:dkey-174n20.2 antikoerper, CAMKK2 antikoerper, calcium/calmodulin dependent protein kinase kinase 2 antikoerper, calcium/calmodulin-dependent protein kinase kinase 2, beta antikoerper, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antikoerper, calcium/calmodulin dependent protein kinase II beta antikoerper, calcium/calmodulin-dependent protein kinase kinase 2 antikoerper, CAMKK2 antikoerper, Camkk2 antikoerper, camk2b1 antikoerper, CAMK2B antikoerper, camkk2 antikoerper
Hintergrund
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.