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CASP5 Antikörper (AA 162-191)

CASP5 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030309
  • Target Alle CASP5 Antikörper anzeigen
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-191
    Reaktivität
    • 43
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 3
    Kaninchen
    Klonalität
    • 33
    • 10
    Polyklonal
    Konjugat
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser CASP5 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 162-191 from the human protein was used as the immunogen for this Caspase-5 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CASP5 Primärantikörper
  • Applikationshinweise
    Titration of the Caspase-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the Caspase-5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Andere Bezeichnung
    Caspase-5 (CASP5 Produkte)
    Synonyme
    ICE(rel)III antikoerper, ICEREL-III antikoerper, ICH-3 antikoerper, CASP5 antikoerper, caspase 5 antikoerper, caspase-5 antikoerper, CASP5 antikoerper, LOC100437308 antikoerper
    Hintergrund
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
    UniProt
    P51878
    Pathways
    Inflammasome
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