CCR1 Antikörper (AA 1-30)

Produktnummer ABIN3030216

Produktdetails anti-CCR1 Antikörper

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Bindungsspezifität: AA 1-30

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CCR1

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Andere Bezeichnung: CCR1 (CCR1 Produkte)

Synonyme: CD191 antikoerper, CKR-1 antikoerper, CKR1 antikoerper, CMKBR1 antikoerper, HM145 antikoerper, MIP1aR antikoerper, SCYAR1 antikoerper, Cmkbr1 antikoerper, Mip-1a-R antikoerper, C-C motif chemokine receptor 1 antikoerper, chemokine (C-C motif) receptor 1 antikoerper, CCR1 antikoerper, Ccr1 antikoerper

Hintergrund: CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

UniProt: P32246