CD46 Antikörper (AA 317-343)

Produktnummer ABIN3030405

Dieses Anti-CD46-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD46 in WB, FACS, ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für CD46 Antikörper (AA 317-343) (ABIN3030405)

Target: CD46

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CD46 Antikörper

Bindungsspezifität: AA 317-343

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 317-343 from the human protein was used as the immunogen for this CD46 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CD46 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CD46 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CD46

Target: CD46

Andere Bezeichnung: CD46

Hintergrund: CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system.

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization