CDK4 Antikörper (AA 273-305)
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- Target Alle CDK4 Antikörper anzeigen
- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
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Bindungsspezifität
- AA 273-305
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDK4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 273-305 from the human protein was used as the immunogen for this CDK4 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CDK4 Primärantikörper
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anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 273-305), (C-Term) antibody
CDK4 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB03154 unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) antibodyKO Validated CDK4 Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 211-303) antibodyCDK4 Reaktivität: Human WB, ELISA, IF, RNAi Wirt: Maus Monoclonal 4F11 unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 6-295) antibodyCDK4 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 272-303), (C-Term) antibodyCDK4 Reaktivität: Ratte WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 201-303) antibodyCDK4 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 241-303) antibodyCDK4 Reaktivität: Human, Maus, Ratte, Schaf WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 272-303) antibodyCDK4 Reaktivität: Human, Ratte ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (N-Term) antibodyCDK4 Reaktivität: Human, Maus, Ratte, Hund WB, IP, IHC (fro), BI Wirt: Maus Monoclonal DCS-35 unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (C-Term) antibodyCDK4 Reaktivität: Human, Ratte, Schaf, Schwein, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the CDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the CDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
- Andere Bezeichnung
- CDK4 (CDK4 Produkte)
- Hintergrund
- CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of the gene have been reported.
- UniProt
- P11802
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, Regulation of Cell Size
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