BIRC3 Antikörper (AA 101-131)

Produktnummer ABIN3030108

Produktdetails anti-BIRC3 Antikörper

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Bindungsspezifität: AA 101-131

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 101-131 from the human protein was used as the immunogen for this cIAP2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the cIAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the cIAP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu BIRC3

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Andere Bezeichnung: cIAP2 (BIRC3 Produkte)

Synonyme: AIP1 antikoerper, API2 antikoerper, CIAP2 antikoerper, HAIP1 antikoerper, HIAP1 antikoerper, MALT2 antikoerper, MIHC antikoerper, RNF49 antikoerper, c-IAP2 antikoerper, Api1 antikoerper, Api2 antikoerper, IAP1 antikoerper, IAP2 antikoerper, MIHB antikoerper, Birc2 antikoerper, HIAP2 antikoerper, MIAP1 antikoerper, MIAP2 antikoerper, cIAP1 antikoerper, cIAP2 antikoerper, cIAP-1 antikoerper, cIAP-2 antikoerper, AW107670 antikoerper, BIRC2 antikoerper, baculoviral IAP repeat containing 3 antikoerper, baculoviral IAP repeat-containing 3 antikoerper, baculoviral IAP repeat-containing protein 3 antikoerper, inhibitor of apoptosis protein-2 antikoerper, BIRC3 antikoerper, Birc3 antikoerper, LOC100399118 antikoerper, OpmnVgp074 antikoerper

Hintergrund: BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.

UniProt: Q13489

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades