CPT1C Antikörper (AA 596-625)

Produktnummer ABIN3030284

Produktdetails anti-CPT1C Antikörper

Target: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Bindungsspezifität: AA 596-625

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPT1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 596-625 from the human protein was used as the immunogen for this CPT1C antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CPT1C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CPT1C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CPT1C

Target: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Andere Bezeichnung: CPT1C (CPT1C Produkte)

Synonyme: 6530437J22Rik antikoerper, 9630004I06Rik antikoerper, CATL1 antikoerper, CPT1-B antikoerper, CPT1P antikoerper, CPTI-B antikoerper, CPTIC antikoerper, CPT IC antikoerper, carnitine palmitoyltransferase 1c antikoerper, carnitine palmitoyltransferase 1C antikoerper, Cpt1c antikoerper, CPT1C antikoerper

Hintergrund: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

UniProt: Q8TCG5

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process