DCLK1 Antikörper (AA 153-181)

Produktnummer ABIN3030771

Produktdetails anti-DCLK1 Antikörper

Target: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Bindungsspezifität: AA 153-181

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 153-181 from the mouse protein was used as the immunogen for this Dclk1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Dclk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Dclk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu DCLK1

Target: DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Andere Bezeichnung: Dclk1 (DCLK1 Produkte)

Synonyme: DCLK1 antikoerper, DCAMKL1 antikoerper, dcamkl1 antikoerper, dclk1 antikoerper, wu:fc51f11 antikoerper, zgc:153709 antikoerper, MGC145348 antikoerper, CL1 antikoerper, CLICK1 antikoerper, DCDC3A antikoerper, DCLK antikoerper, 1700113D08Rik antikoerper, 2810480F11Rik antikoerper, AI836758 antikoerper, Click-I antikoerper, Cpg16 antikoerper, Dcamkl1 antikoerper, Dcl antikoerper, Dclk antikoerper, mKIAA0369 antikoerper, Ania4 antikoerper, doublecortin like kinase 1 antikoerper, doublecortin-like kinase 1a antikoerper, serine/threonine-protein kinase DCLK1 antikoerper, doublecortin-like kinase 2 antikoerper, doublecortin-like kinase 1 antikoerper, DCLK1 antikoerper, dclk1a antikoerper, LOC587664 antikoerper, dclk2 antikoerper, LOC100539645 antikoerper, Dclk1 antikoerper

Hintergrund: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been found, but the biological validity of some variants has not been determined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.

UniProt: Q9JLM8