RCAN1 Antikörper (AA 222-252)
-
- Target Alle RCAN1 Antikörper anzeigen
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
-
Bindungsspezifität
- AA 222-252
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RCAN1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Bovine, Hamster
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RCAN1 Primärantikörper
-
-
- Applikationshinweise
- Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Target
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Andere Bezeichnung
- DSCR1 (RCAN1 Produkte)
- Hintergrund
- DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
- UniProt
- P53805
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
-