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DUSP6 Antikörper (AA 59-88)

DUSP6 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030776
  • Target Alle DUSP6 Antikörper anzeigen
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 59-88
    Reaktivität
    • 88
    • 57
    • 51
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 76
    • 11
    • 2
    • 1
    Kaninchen
    Klonalität
    • 72
    • 18
    Polyklonal
    Konjugat
    • 38
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP6 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 33
    • 13
    • 13
    • 11
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität (Details)
    Expected species reactivity: Bovine
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 59-88 from the human protein was used as the immunogen for this DUSP6 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DUSP6 Primärantikörper
  • Applikationshinweise
    Titration of the DUSP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the DUSP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    Andere Bezeichnung
    DUSP6 (DUSP6 Produkte)
    Synonyme
    HH19 antikoerper, MKP3 antikoerper, PYST1 antikoerper, 1300019I03Rik antikoerper, MKP-3 antikoerper, Mkp3 antikoerper, wu:fd99d09 antikoerper, mkp3 antikoerper, pyst1 antikoerper, DUSP6 antikoerper, dusp6 antikoerper, dual specificity phosphatase 6 antikoerper, dual specificity phosphatase 6 L homeolog antikoerper, Dual specificity protein phosphatase 6 antikoerper, DUSP6 antikoerper, Dusp6 antikoerper, dusp6 antikoerper, dusp6.L antikoerper, dus6 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
    UniProt
    Q16828
    Pathways
    Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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