DYRK1A Antikörper (AA 107-136)
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- Target Alle DYRK1A Antikörper anzeigen
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
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Bindungsspezifität
- AA 107-136
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DYRK1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat, Xenopus
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 107-136 from the human protein was used as the immunogen for this DYRK1A antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product DYRK1A Primärantikörper
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- Applikationshinweise
- Titration of the DYRK1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000,IHC (Paraffin): 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the DYRK1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
- Andere Bezeichnung
- DYRK1A (DYRK1A Produkte)
- Hintergrund
- DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.
- UniProt
- Q13627
- Pathways
- Mitotic G1-G1/S Phases
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