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DYRK1A Antikörper (AA 107-136)

DYRK1A Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030777
  • Target Alle DYRK1A Antikörper anzeigen
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-136
    Reaktivität
    • 68
    • 29
    • 22
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 62
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 65
    • 4
    Polyklonal
    Konjugat
    • 38
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DYRK1A Antikörper ist unkonjugiert
    Applikation
    • 69
    • 37
    • 13
    • 13
    • 13
    • 11
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Rat, Xenopus
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 107-136 from the human protein was used as the immunogen for this DYRK1A antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DYRK1A Primärantikörper
  • Applikationshinweise
    Titration of the DYRK1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the DYRK1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    Andere Bezeichnung
    DYRK1A (DYRK1A Produkte)
    Hintergrund
    DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.
    UniProt
    Q13627
    Pathways
    Mitotic G1-G1/S Phases
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