EPH Receptor A3 Antikörper (AA 115-144)

Produktnummer ABIN3030819

Produktdetails anti-EPH Receptor A3 Antikörper

Target: EPH Receptor A3 (EPHA3)

Bindungsspezifität: AA 115-144

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Purified

Immunogen: A portion of amino acids 115-144 from the human protein was used as the immunogen for this EphA3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the EphA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the EphA3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Andere Bezeichnung: EphA3 (EPHA3 Produkte)

Synonyme: EK4 antikoerper, ETK antikoerper, ETK1 antikoerper, HEK antikoerper, HEK4 antikoerper, TYRO4 antikoerper, EPHA3 antikoerper, AW492086 antikoerper, Cek4 antikoerper, End3 antikoerper, Hek antikoerper, Hek4 antikoerper, Mek4 antikoerper, Tyro4 antikoerper, CEK4 antikoerper, EPH receptor A3 antikoerper, ephrin type-A receptor 3 antikoerper, Eph receptor A3 antikoerper, EPHA3 antikoerper, LOC100439679 antikoerper, Epha3 antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

UniProt: P29320

Pathways: RTK Signalweg, Regulation of Cell Size