EPH Receptor B2 Antikörper (AA 1021-1050)

Produktnummer ABIN3030826

Produktdetails anti-EPH Receptor B2 Antikörper

Target: EPH Receptor B2 (EPHB2)

Bindungsspezifität: AA 1021-1050

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Purified

Immunogen: A portion of amino acids 1021-1050 from the human protein was used as the immunogen for this EphB2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the EphB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the EphB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu EPH Receptor B2

Target: EPH Receptor B2 (EPHB2)

Andere Bezeichnung: EphB2 (EPHB2 Produkte)

Synonyme: CAPB antikoerper, DRT antikoerper, EK5 antikoerper, EPHT3 antikoerper, ERK antikoerper, Hek5 antikoerper, PCBC antikoerper, Tyro5 antikoerper, ERK2 antikoerper, ERT1 antikoerper, MAPK2 antikoerper, P42MAPK antikoerper, PRKM1 antikoerper, PRKM2 antikoerper, p38 antikoerper, p40 antikoerper, p41 antikoerper, p41mapk antikoerper, RGD1564232 antikoerper, Cek5 antikoerper, Drt antikoerper, ETECK antikoerper, Erk antikoerper, Nuk antikoerper, Prkm5 antikoerper, Qek5 antikoerper, Sek3 antikoerper, cek5 antikoerper, ephb2 antikoerper, xEphB2 antikoerper, si:ch73-160e9.1 antikoerper, tpx2 antikoerper, wu:fb09e10 antikoerper, wu:fc64a03 antikoerper, wu:fi18g12 antikoerper, zgc:112296 antikoerper, EPH receptor B2 antikoerper, mitogen-activated protein kinase 1 antikoerper, Eph receptor B2 antikoerper, EPH receptor B2 L homeolog antikoerper, eph receptor B2a antikoerper, eph receptor B2b antikoerper, EPHB2 antikoerper, MAPK1 antikoerper, Ephb2 antikoerper, ephb2.L antikoerper, ephb2a antikoerper, ephb2b antikoerper

Hintergrund: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.

UniProt: P29323

Pathways: RTK Signalweg, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine