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FKBP1A Antikörper (AA 43-74)

FKBP1A Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030968
  • Target Alle FKBP1A Antikörper anzeigen
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    Bindungsspezifität
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 43-74
    Reaktivität
    • 58
    • 29
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 56
    • 9
    Kaninchen
    Klonalität
    • 48
    • 17
    Polyklonal
    Konjugat
    • 29
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser FKBP1A Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 17
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Rat, Bovine, Rabbit
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 43-74 from the human protein was used as the immunogen for this FKBP12 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product FKBP1A Primärantikörper
  • Applikationshinweise
    Titration of the FKBP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the FKBP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    Andere Bezeichnung
    FKBP12 (FKBP1A Produkte)
    Hintergrund
    FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
    UniProt
    P62942
    Pathways
    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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