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Glypican 3 Antikörper (AA 21-50)

GPC3 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031098
  • Target Alle Glypican 3 (GPC3) Antikörper anzeigen
    Glypican 3 (GPC3)
    Bindungsspezifität
    • 20
    • 16
    • 12
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-50
    Reaktivität
    • 143
    • 48
    • 45
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 88
    • 55
    • 1
    Kaninchen
    Klonalität
    • 74
    • 69
    • 1
    Polyklonal
    Konjugat
    • 58
    • 12
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glypican 3 Antikörper ist unkonjugiert
    Applikation
    • 82
    • 78
    • 63
    • 44
    • 35
    • 26
    • 17
    • 16
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 21-50 from the human protein was used as the immunogen for this Glypican 3 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GPC3 Primärantikörper
  • Applikationshinweise
    Titration of the Glypican 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the Glypican 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Glypican 3 (GPC3)
    Andere Bezeichnung
    Glypican 3 (GPC3 Produkte)
    Synonyme
    GPC3 antikoerper, sgb antikoerper, dgsx antikoerper, sdys antikoerper, sgbs antikoerper, oci-5 antikoerper, sgbs1 antikoerper, DGSX antikoerper, GTR2-2 antikoerper, MXR7 antikoerper, OCI-5 antikoerper, SDYS antikoerper, SGB antikoerper, SGBS antikoerper, SGBS1 antikoerper, Glypican-3 antikoerper, glypican 3 antikoerper, gpc3 antikoerper, GPC3 antikoerper, Gpc3 antikoerper
    Hintergrund
    GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
    UniProt
    P51654
    Pathways
    Glycosaminoglycan Metabolic Process
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