HMGA2 Antikörper (AA 64-92)

Produktnummer ABIN3031201

Produktdetails anti-HMGA2 Antikörper

Target: HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

Bindungsspezifität: AA 64-92

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 64-92 from the human protein was used as the immunogen for this HMGA2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the HMGA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the HMGA2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu HMGA2

Target: HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

Andere Bezeichnung: HMGA2 (HMGA2 Produkte)

Synonyme: 9430083A20Rik antikoerper, HMGI-C antikoerper, Hmgic antikoerper, pg antikoerper, pygmy antikoerper, wu:fc27f12 antikoerper, wu:fc28f02 antikoerper, wu:fc57d12 antikoerper, zgc:77719 antikoerper, BABL antikoerper, LIPO antikoerper, HMGIC antikoerper, STQTL9 antikoerper, high mobility group AT-hook 2 antikoerper, Hmga2 antikoerper, hmga2 antikoerper, HMGA2 antikoerper

Hintergrund: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P52926

Pathways: Positive Regulation of Response to DNA Damage Stimulus