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SYVN1 Antikörper (AA 58-88)

SYVN1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029081
  • Target Alle SYVN1 Antikörper anzeigen
    SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
    Bindungsspezifität
    • 16
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 58-88
    Reaktivität
    • 57
    • 35
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 2
    • 2
    Kaninchen
    Klonalität
    • 56
    • 2
    Polyklonal
    Konjugat
    • 28
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SYVN1 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 21
    • 15
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität (Details)
    Expected species reactivity: Mouse, Xenopus
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 58-88 from the human protein was used as the immunogen for this HRD1 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SYVN1 Primärantikörper
  • Applikationshinweise
    Titration of the HRD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the HRD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
    Andere Bezeichnung
    HRD1 (SYVN1 Produkte)
    Synonyme
    DER3 antikoerper, HRD1 antikoerper, hrd1 antikoerper, 1200010C09Rik antikoerper, AW211966 antikoerper, C85322 antikoerper, D530017H19Rik antikoerper, Hrd1 antikoerper, RGD1310488 antikoerper, syvn1 antikoerper, syvn1-a antikoerper, syvn1-b antikoerper, wu:fk91f10 antikoerper, zgc:55735 antikoerper, zgc:77108 antikoerper, synoviolin 1 antikoerper, synovial apoptosis inhibitor 1, synoviolin antikoerper, synoviolin 1 S homeolog antikoerper, SYVN1 antikoerper, syvn1 antikoerper, Syvn1 antikoerper, syvn1.S antikoerper
    Hintergrund
    HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Synoviolin/Hrd1 (expressed in rheumatoid synovium) is reported to be a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.
    UniProt
    Q86TM6
    Pathways
    ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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