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IGHM Antikörper (AA 103-131)

IGHM Reaktivität: Human IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031293
  • Target Alle IGHM Produkte
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    Bindungsspezifität
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 103-131
    Reaktivität
    • 25
    • 1
    • 1
    Human
    Wirt
    • 14
    • 11
    Kaninchen
    Klonalität
    • 17
    • 8
    Polyklonal
    Konjugat
    • 21
    • 1
    • 1
    • 1
    • 1
    Dieser IGHM Antikörper ist unkonjugiert
    Applikation
    • 12
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 103-131 from the human protein was used as the immunogen for this IGHM antibody.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    Titration of the IGHM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the IGHM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    Andere Bezeichnung
    IGHM (IGHM Produkte)
    Synonyme
    AI326478 antikoerper, Igh-6 antikoerper, Igh-M antikoerper, Igh6 antikoerper, Igm antikoerper, muH antikoerper, ighm1 antikoerper, wu:fj14a08 antikoerper, zgc:101769 antikoerper, AGM1 antikoerper, MU antikoerper, VH antikoerper, immunoglobulin heavy constant mu antikoerper, Ighm antikoerper, ighm antikoerper, IGHM antikoerper
    Hintergrund
    IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30 % of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts. [UniProt]
    UniProt
    P01871
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