IL-10 Antikörper (AA 27-53)
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- Target Alle IL-10 (IL10) Antikörper anzeigen
- IL-10 (IL10) (Interleukin 10 (IL10))
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Bindungsspezifität
- AA 27-53
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Kreuzreaktivität (Details)
- Expected species reactivity: Primate
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IL10 Primärantikörper
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- Applikationshinweise
- Titration of the IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the IL-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Andere Bezeichnung
- IL-10 (IL10 Produkte)
- Synonyme
- CSIF antikoerper, GVHDS antikoerper, IL-10 antikoerper, IL10A antikoerper, TGIF antikoerper, Il-10 antikoerper, IL10X antikoerper, interleukin 10 antikoerper, IL10 antikoerper, Il10 antikoerper
- Hintergrund
- The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
- UniProt
- P22301
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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