IRAK1 Antikörper (AA 683-712)

Produktnummer ABIN3031490

Produktdetails anti-IRAK1 Antikörper

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Bindungsspezifität: AA 683-712

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Purified

Immunogen: A portion of amino acids 683-712 from the human protein was used as the immunogen for this IRAK antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the IRAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IRAK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu IRAK1

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Andere Bezeichnung: IRAK (IRAK1 Produkte)

Synonyme: IRAK1 antikoerper, IRAK antikoerper, pelle antikoerper, AA408924 antikoerper, IRAK-1 antikoerper, IRAK1-S antikoerper, Il1rak antikoerper, Plpk antikoerper, mPLK antikoerper, RGD1563841 antikoerper, interleukin 1 receptor associated kinase 1 antikoerper, interleukin-1 receptor-associated kinase 1 antikoerper, IRAK1 antikoerper, irak1 antikoerper, Irak1 antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

UniProt: P51617

Pathways: NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades