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JMJD2D Antikörper (AA 484-516)

KDM4D Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031654
  • Target Alle JMJD2D (KDM4D) Antikörper anzeigen
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Bindungsspezifität
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 484-516
    Reaktivität
    • 33
    • 3
    • 2
    • 1
    Human
    Wirt
    • 33
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JMJD2D Antikörper ist unkonjugiert
    Applikation
    • 22
    • 17
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 484-516 from the human protein was used as the immunogen for this JMJD2D antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product KDM4D Primärantikörper
  • Applikationshinweise
    Titration of the JMJD2D antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the JMJD2D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Andere Bezeichnung
    JMJD2D (KDM4D) (KDM4D Produkte)
    Synonyme
    JMJD2D antikoerper, 4932416A15 antikoerper, Jmjd2d antikoerper, KDM4D antikoerper, lysine demethylase 4D antikoerper, lysine-specific demethylase 4D antikoerper, lysine (K)-specific demethylase 4D antikoerper, KDM4D antikoerper, LOC524768 antikoerper, Kdm4d antikoerper, LOC617971 antikoerper, LOC100067461 antikoerper, LOC698455 antikoerper, LOC100514356 antikoerper
    Hintergrund
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    UniProt
    Q6B0I6
    Pathways
    Warburg Effekt
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