L1CAM Antikörper (AA 1154-1182)
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- Target Alle L1CAM Antikörper anzeigen
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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Bindungsspezifität
- AA 1154-1182
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser L1CAM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität (Details)
- Expected species reactivity: Rat
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A portion of amino acids 1154-1182 from the human protein was used as the immunogen for this L1CAM antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product L1CAM Primärantikörper
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- Applikationshinweise
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Titration of the L1CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. Cleavage by ADAM10 results in 180 and 40 kDa bands while cleavage by Plasmin results in 140 and 80 kDa bands.\. Western blot: 1:1000 (1)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the L1CAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- Andere Bezeichnung
- L1CAM (L1CAM Produkte)
- Synonyme
- l1cam-a antikoerper, CAML1 antikoerper, CD171 antikoerper, HSAS antikoerper, HSAS1 antikoerper, MASA antikoerper, MIC5 antikoerper, N-CAM-L1 antikoerper, N-CAML1 antikoerper, NCAM-L1 antikoerper, S10 antikoerper, SPG1 antikoerper, L1 antikoerper, Hsas antikoerper, Hyd antikoerper, NCAML1 antikoerper, L1 cell adhesion molecule S homeolog antikoerper, L1 cell adhesion molecule antikoerper, l1cam.S antikoerper, L1CAM antikoerper, L1cam antikoerper
- Hintergrund
- L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
- UniProt
- P32004
- Pathways
- Synaptic Membrane
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