Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

LC3B Antikörper (AA 77-106)

MAP1LC3B Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029808
  • Target Alle LC3B (MAP1LC3B) Antikörper anzeigen
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    Bindungsspezifität
    • 14
    • 13
    • 10
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 77-106
    Reaktivität
    • 108
    • 46
    • 31
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 98
    • 13
    • 7
    Kaninchen
    Klonalität
    • 103
    • 16
    Polyklonal
    Konjugat
    • 72
    • 10
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser LC3B Antikörper ist unkonjugiert
    Applikation
    • 66
    • 47
    • 33
    • 28
    • 20
    • 14
    • 12
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 77-106 from the human protein was used as the immunogen for this LC3B antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MAP1LC3B Primärantikörper
  • Applikationshinweise
    Titration of the LC3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the LC3B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    Andere Bezeichnung
    LC3B (MAP1LC3B Produkte)
    Hintergrund
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3b is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
    UniProt
    Q9GZQ8
    Pathways
    Autophagie
Sie sind hier:
Kundenservice