MCL-1 Antikörper (AA 191-226)

Produktnummer ABIN3031299

Produktdetails anti-MCL-1 Antikörper

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Bindungsspezifität: AA 191-226

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCL-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: Purified

Immunogen: A portion of amino acids 191-226 from the human protein was used as the immunogen for this MCL1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MCL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Andere Bezeichnung: MCL1 (MCL1 Produkte)

Synonyme: BCL2L3 antikoerper, EAT antikoerper, MCL1-ES antikoerper, MCL1L antikoerper, MCL1S antikoerper, Mcl-1 antikoerper, TM antikoerper, bcl2-L-3 antikoerper, mcl1/EAT antikoerper, AW556805 antikoerper, mcl-1 antikoerper, fb72f02 antikoerper, wu:fb70a08 antikoerper, wu:fb72f02 antikoerper, zfMLP1 antikoerper, zfMcl-1a antikoerper, zgc:109835 antikoerper, zgc:109763 antikoerper, E3 antikoerper, E3-2 antikoerper, RNE3 antikoerper, RNU107 antikoerper, SNORA63A antikoerper, elF-4AII antikoerper, MCL1, BCL2 family apoptosis regulator antikoerper, myeloid cell leukemia sequence 1 antikoerper, MCL1, BCL2 family apoptosis regulator a antikoerper, MCL1, BCL2 family apoptosis regulator b antikoerper, small nucleolar RNA, H/ACA box 63 antikoerper, MCL1 antikoerper, Mcl1 antikoerper, mcl1a antikoerper, mcl1b antikoerper, SNORA63 antikoerper

Hintergrund: The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

UniProt: Q07820

Pathways: MAPK Signalweg