Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

LRP2 Antikörper (AA 4626-4655)

LRP2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031639
  • Target Alle LRP2 Antikörper anzeigen
    LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
    Bindungsspezifität
    • 16
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4626-4655
    Reaktivität
    • 60
    • 31
    • 15
    • 3
    • 3
    Human
    Wirt
    • 57
    • 3
    Kaninchen
    Klonalität
    • 58
    • 3
    Polyklonal
    Konjugat
    • 18
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LRP2 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 17
    • 17
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 4626-4655 from the human protein was used as the immunogen for this Megalin antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product LRP2 Primärantikörper
  • Applikationshinweise
    Titration of the Megalin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the Megalin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
    Andere Bezeichnung
    Megalin (LRP2 Produkte)
    Synonyme
    im:680590 antikoerper, lrp2 antikoerper, dbs antikoerper, gp330 antikoerper, megalin antikoerper, DBS antikoerper, GP330 antikoerper, AI315343 antikoerper, AW536255 antikoerper, D230004K18Rik antikoerper, Gp330 antikoerper, Megalin antikoerper, LDL receptor related protein 2 antikoerper, low density lipoprotein receptor-related protein 2a antikoerper, low density lipoprotein receptor-related protein 2 antikoerper, low-density lipoprotein receptor-related protein 2 antikoerper, LDL receptor related protein 2 L homeolog antikoerper, LRP2 antikoerper, lrp2a antikoerper, LRP2.3 antikoerper, lrp2.L antikoerper, LOC100183506 antikoerper, lrp2 antikoerper, Lrp2 antikoerper
    Hintergrund
    Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration (1). Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes (2). All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family (3).
    UniProt
    P98164
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport
Sie sind hier:
Kundenservice