MIB1 Antikörper (AA 13-42)

Produktnummer ABIN3031774

Produktdetails anti-MIB1 Antikörper

Target: MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))

Bindungsspezifität: AA 13-42

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIB1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Zebrafish, Xenopus

Aufreinigung: Purified

Immunogen: A portion of amino acids 13-42 from the human protein was used as the immunogen for this Mib1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Mib1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:20-1:100,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Mib1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu MIB1

Target: MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))

Andere Bezeichnung: Mib1 (Mindbomb) (MIB1 Produkte)

Synonyme: DIP-1 antikoerper, DIP1 antikoerper, LVNC7 antikoerper, MIB antikoerper, ZZANK2 antikoerper, ZZZ6 antikoerper, E430019M12Rik antikoerper, Mib antikoerper, mKIAA1323 antikoerper, dip-1 antikoerper, mib antikoerper, mindbomb antikoerper, cg5841 antikoerper, chunp6889 antikoerper, fe47f05 antikoerper, im:7148100 antikoerper, mib1 antikoerper, wu:fe47f05 antikoerper, CG5841 antikoerper, D-mib antikoerper, D-mib1 antikoerper, Dmel\CG5841 antikoerper, Dmib antikoerper, MIB1 antikoerper, Mib1 antikoerper, dmib1 antikoerper, l(3)72CDa antikoerper, l(3)72Db antikoerper, mib1/2 antikoerper, mind-bomb antikoerper, mindbomb E3 ubiquitin protein ligase 1 antikoerper, mindbomb E3 ubiquitin protein ligase 1 L homeolog antikoerper, mind bomb 1 antikoerper, MIB1 antikoerper, Mib1 antikoerper, mib1.L antikoerper, mib1 antikoerper

Hintergrund: MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.

UniProt: Q86YT6

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion