MAP4K4 Antikörper (AA 618-649)
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- Target Alle MAP4K4 Antikörper anzeigen
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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Bindungsspezifität
- AA 618-649
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAP4K4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 618-649 from the human protein was used as the immunogen for this NIK antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MAP4K4 Primärantikörper
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- Applikationshinweise
- Titration of the NIK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the NIK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
- Andere Bezeichnung
- NIK (Nck-Interacting Kinase) (MAP4K4 Produkte)
- Synonyme
- FLH21957 antikoerper, HGK antikoerper, MEKKK4 antikoerper, NIK antikoerper, 9430080K19Rik antikoerper, AU043147 antikoerper, AU045934 antikoerper, AW046177 antikoerper, Nik antikoerper, mitogen-activated protein kinase kinase kinase kinase 4 antikoerper, MAP4K4 antikoerper, Map4k4 antikoerper
- Hintergrund
- HGK/NIK, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK/NIK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
- UniProt
- O95819
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