NLRP10 Antikörper (AA 466-494)

Produktnummer ABIN3032014

Produktdetails anti-NLRP10 Antikörper

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Bindungsspezifität: AA 466-494

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP10 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 466-494 from the human protein was used as the immunogen for this NLRP10 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NLRP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NLRP10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Andere Bezeichnung: NLRP10 (NLRP10 Produkte)

Synonyme: CLR11.1 antikoerper, NALP10 antikoerper, NOD8 antikoerper, PAN5 antikoerper, PYNOD antikoerper, 6430548I20Rik antikoerper, Nalp10 antikoerper, Napl10 antikoerper, Pynod antikoerper, NLR family pyrin domain containing 10 antikoerper, NLR family, pyrin domain containing 10 antikoerper, NLRP10 antikoerper, Nlrp10 antikoerper

Hintergrund: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].

UniProt: Q86W26

Pathways: Inflammasome