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NLRP3 Antikörper (AA 65-91)

NLRP3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032020
  • Target Alle NLRP3 Antikörper anzeigen
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-91
    Reaktivität
    • 84
    • 50
    • 32
    • 17
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 80
    • 11
    • 2
    • 1
    Kaninchen
    Klonalität
    • 79
    • 15
    Polyklonal
    Konjugat
    • 43
    • 9
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NLRP3 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 38
    • 16
    • 13
    • 13
    • 11
    • 9
    • 8
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 65-91 from the human protein was used as the immunogen for this NLRP3 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NLRP3 Primärantikörper
  • Applikationshinweise
    Titration of the NLRP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the NLRP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    Andere Bezeichnung
    NLRP3 (NLRP3 Produkte)
    Synonyme
    CIAS1 antikoerper, Nalp3 antikoerper, avp antikoerper, cias1 antikoerper, nalp3 antikoerper, pypaf1 antikoerper, agtavprl antikoerper, AGTAVPRL antikoerper, AII antikoerper, AVP antikoerper, C1orf7 antikoerper, CLR1.1 antikoerper, FCAS antikoerper, FCU antikoerper, MWS antikoerper, NALP3 antikoerper, PYPAF1 antikoerper, AII/AVP antikoerper, Cias1 antikoerper, Mmig1 antikoerper, Pypaf1 antikoerper, NLR family pyrin domain containing-like antikoerper, NLR family pyrin domain containing 3 antikoerper, NLR family, pyrin domain containing 3 L homeolog antikoerper, NLR family, pyrin domain containing 3 antikoerper, NLRPL antikoerper, NLRP3 antikoerper, nlrp3.L antikoerper, Nlrp3 antikoerper
    Hintergrund
    NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
    UniProt
    Q96P20
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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