NLRP6 Antikörper (AA 168-197)

Produktnummer ABIN3032023

Produktdetails anti-NLRP6 Antikörper

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Bindungsspezifität: AA 168-197

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this NLRP6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NLRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NLRP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NLRP6

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Andere Bezeichnung: NLRP6 (NLRP6 Produkte)

Synonyme: NLRP6 antikoerper, NALP6 antikoerper, AVR antikoerper, CLR11.4 antikoerper, NAVR antikoerper, NAVR/AVR antikoerper, PAN3 antikoerper, PYPAF5 antikoerper, AI504961 antikoerper, Avr antikoerper, Nalp6 antikoerper, Navr antikoerper, Navr/Avr antikoerper, Pypaf5 antikoerper, NLR family pyrin domain containing 6 antikoerper, NLR family, pyrin domain containing 6 antikoerper, NLRP6 antikoerper, Nlrp6 antikoerper

Hintergrund: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1, also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.

UniProt: P59044

Pathways: Inflammasome