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NOTCH3 Antikörper (AA 2291-2321)

NOTCH3 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032032
  • Target Alle NOTCH3 Antikörper anzeigen
    NOTCH3 (Notch 3 (NOTCH3))
    Bindungsspezifität
    • 14
    • 10
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 2291-2321
    Reaktivität
    • 52
    • 17
    • 11
    • 1
    Human, Maus
    Wirt
    • 33
    • 19
    • 4
    • 1
    • 1
    Kaninchen
    Klonalität
    • 37
    • 22
    Polyklonal
    Konjugat
    • 31
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NOTCH3 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 24
    • 21
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 2291-2321 from the human protein was used as the immunogen for this NOTCH3 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NOTCH3 Primärantikörper
  • Applikationshinweise
    Titration of the NOTCH3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the NOTCH3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Andere Bezeichnung
    NOTCH3 (NOTCH3 Produkte)
    Synonyme
    CADASIL antikoerper, CASIL antikoerper, IMF2 antikoerper, AW229011 antikoerper, N3 antikoerper, hpbk antikoerper, fa14b08 antikoerper, notch5 antikoerper, wu:fa14b08 antikoerper, notch 3 antikoerper, NOTCH3 antikoerper, Notch3 antikoerper, notch3 antikoerper
    Hintergrund
    NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
    UniProt
    Q9UM47
    Pathways
    Notch Signalweg
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