Neuregulin 1 Antikörper (AA 198-229)
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- Target Alle Neuregulin 1 (NRG1) Antikörper anzeigen
- Neuregulin 1 (NRG1)
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Bindungsspezifität
- AA 198-229
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Neuregulin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Aufreinigung
- Purified
- Immunogen
- A portion of amino acids 198-229 from the human protein was used as the immunogen for this NRG1 antibody.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NRG1 Primärantikörper
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anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody
NRG1 Reaktivität: Human, Ratte WB, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (C-Term) antibodyNRG1 Reaktivität: Human, Ratte, Maus WB, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (N-Term) antibodyNRG1 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 221-320) antibodyNRG1 Reaktivität: Human, Ratte, Maus WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 198-229) antibodyNRG1 Reaktivität: Human FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01275-01276 unconjugated
anti-Neuregulin 1 (NRG1) (AA 1-241) antibodyNRG1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 21-242) antibodyNRG1 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal NRG1-2710 unconjugated
anti-Neuregulin 1 (NRG1) antibodyNRG1 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 21-242) antibodyNRG1 Reaktivität: Human ELISA, IF, Coat Wirt: Maus Monoclonal NRG1-2752 unconjugated
anti-Neuregulin 1 (NRG1) (AA 54-163) antibodyNRG1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Titration of the NRG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot the NRG1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- Neuregulin 1 (NRG1)
- Andere Bezeichnung
- NRG1 (NRG1 Produkte)
- Hintergrund
- Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains, and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
- UniProt
- Q02297
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation
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