NUP50 Antikörper (AA 432-461)

Produktnummer ABIN3032078

Produktdetails anti-NUP50 Antikörper

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Bindungsspezifität: AA 432-461

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Rat

Aufreinigung: Purified

Immunogen: A portion of amino acids 432-461 from the human protein was used as the immunogen for this NUP50 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the NUP50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NUP50 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Andere Bezeichnung: NUP50 (NUP50 Produkte)

Synonyme: wu:fa56e03 antikoerper, wu:fb78a08 antikoerper, GB18194 antikoerper, npap60 antikoerper, npap60l antikoerper, Nup50 antikoerper, Rtp60 antikoerper, 1700030K07Rik antikoerper, AI413123 antikoerper, Npap60 antikoerper, NPAP60 antikoerper, NPAP60L antikoerper, nucleoporin 50 antikoerper, nuclear pore complex protein Nup50 antikoerper, nucleoporin 50kDa S homeolog antikoerper, nucleoporin 50kDa antikoerper, nup50 antikoerper, LOC410864 antikoerper, NUP50 antikoerper, nup50.S antikoerper, CpipJ_CPIJ012737 antikoerper, Nup50 antikoerper

Hintergrund: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.

UniProt: Q9UKX7

Pathways: Tube Formation