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P-Glycoprotein Antikörper (AA 647-677)

Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032111
  • Target Alle P-Glycoprotein Produkte
    P-Glycoprotein
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    AA 647-677
    Reaktivität
    • 21
    • 10
    • 9
    • 2
    Human
    Wirt
    • 15
    • 7
    Kaninchen
    Klonalität
    • 15
    • 6
    • 1
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser P-Glycoprotein Antikörper ist unkonjugiert
    Applikation
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 647-677 from the human protein was used as the immunogen for this P-Glycoprotein antibody.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    Titration of the P-Glycoprotein antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the P-Glycoprotein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    P-Glycoprotein
    Abstract
    P-Glycoprotein Produkte
    Synonyme
    ABC20 antikoerper, CD243 antikoerper, CLCS antikoerper, GP170 antikoerper, MDR1 antikoerper, P-GP antikoerper, PGY1 antikoerper, Abcb1 antikoerper, Mdr1a antikoerper, ABCB1 antikoerper, ABCB4 antikoerper, CMDR1 antikoerper, xemdr antikoerper, ATP binding cassette subfamily B member 1 antikoerper, ATP binding cassette subfamily B member 1A antikoerper, ATP binding cassette subfamily B member 1 L homeolog antikoerper, ABCB1 antikoerper, Abcb1a antikoerper, abcb1.L antikoerper
    Hintergrund
    The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
    UniProt
    P08183
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